Immunoregulatory functions of immune complexes in vaccine and therapy

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Immunoregulatory functions of immune complexes in vaccine and therapy

Clinical and experimental preparations of IgG/soluble antigen complexes, as well as those formed following antibody therapy in vivo, are multifaceted immune regulators. These immune complexes (ICs) have been tested in humans and animal models, mostly in forms of experimental or clinical vaccination, for at least a century. With intensified research on Fcγ receptor-mediated immune modulation, as...

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ژورنال

عنوان ژورنال: EMBO Molecular Medicine

سال: 2016

ISSN: 1757-4676,1757-4684

DOI: 10.15252/emmm.201606593